加入收藏
百奥莱博公司客服电话百奥莱博QQ百奥莱博QQ百奥莱博QQ
百奥莱博公司微信服务号

产品目录

KU70/XRCC6抗体图片
产品货号:
Z37118
中文名称:
KU70/XRCC6抗体
英文名称:
Anti-KU70/XRCC6 Antibody (Clone#9B6)
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-KU70/XRCC6 Antibody (Clone#9B6)
指标别名5 dRP lyase Ku70;70kDa subunit of Ku antigen;CTC75;CTCBF;DNA repair protein XRCC6;G22P1;KU70;ML8;Thyroid lupus autoantigen;TLAA;XRCC6
克隆性Monoclonal
检验物种human
应用范围WB,IHC,ICC/IF,FCM
基因名称XRCC6
克隆号9B6
抗体来源Mouse
抗体类型IgG2b
免疫原A synthetic peptide corresponding to a sequence at C-terminus of human Ku70 (464-496aa AIVEKLRFTYRSDSFENPVLQQHFRNLEALALD),different from the related mouse sequence by one amino acid.
实际分子量70KD
成分500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol.
纯化方式protein G purified.
浓度500μg/mL
产品形态溶液
保存条件12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing.
背景资料XRCC6 (X-Ray Repair,Complementing Defective,In Chinese Hamster,6),also called Ku70,G22P1 or TLAA,is a protein that in humans,is encoded by the XRCC6 gene.In addition,the XRCC6 gene encodes subunit p70 of the p70/p80 autoantigen which consists of 2 proteins of molecular mass of approximately 70,000 and 80,000 daltons that dimerize to form a 10 S DNA-binding complex.The XRCC6 gene is mapped to 22q13.2.XRCC6 and Mre11 are differentially expressed during meiosis.XRCC6 interacts with Baxa,a mediator of mitochondrial-dependent apoptosis.Disruption of both FANCC and XRCC6 suppressed sensitivity to crosslinking agents,diminished chromosome breaks,and reversed defective homologous recombination.Ku70 binds directly to free DNA ends,committing them to NHEJ repair.In early meiotic prophase,however,when meiotic recombination is most probably initiated,Mre11 was abundant,whereas XRCC6 was not detectable.
Uniprot IDP12956
推荐配套试剂Biorab recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (ZN1928) for Western blot,and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (ZN1866) for IHC(P) and ICC.
基因名全称X-ray repair complementing defective repair in Chinese hamster cells 6
蛋白名全称X-ray repair cross-complementing protein 6
推荐稀释比
Western blot(WB) 1:500~2000
Immunohistochemistry in paraffin section (IHC) 1:50~400
Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50~400
Flow cytometry (FCM) 1~3μg/1×106 cells
(Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user.

相关搜索:KU70/XRCC6抗体KU70抗体XRCC6单抗Anti-KU70/XRCC6 Antibody (Clone#9B6)
首页 |  关于我们 |  联系我们 |  在线咨询 |  网站地图
北京百奥莱博科技有限公司 京ICP备14007103号-3